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5' 5-Methyl dC

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5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details
MW:303.2
Mod Code:/5Me-dC/
Absorbance Max:277 nm
Extinction Coefficient
(At Absorbance max):
9000
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo 49,00 € EUR Add To Order
250 nmole DNA Oligo 63,00 € EUR Add To Order
1 umole DNA Oligo 99,00 € EUR Add To Order
2 µmole DNA Oligo 123,00 € EUR Add To Order
5 umole DNA Oligo 221,00 € EUR Add To Order
10 umole DNA Oligo 411,00 € EUR Add To Order
100 nmole RNA Oligo 49,00 € EUR Add To Order
250 nmole RNA Oligo 63,00 € EUR Add To Order
1 umole RNA Oligo 99,00 € EUR Add To Order
5 umole RNA Oligo 247,00 € EUR Add To Order
10 umole RNA Oligo 411,00 € EUR Add To Order
100 nmole DNA Plate Oligo 49,00 € EUR Add To Order
250 nmole DNA Plate Oligo 63,00 € EUR Add To Order
1 umole DNA Plate Oligo 99,00 € EUR Add To Order
4 nmole Ultramer™ DNA Oligo 56,00 € EUR Add To Order
4 nmole Ultramer™ DNA Plate Oligo 56,00 € EUR Add To Order
20 nmole Ultramer™ DNA Oligo 63,00 € EUR Add To Order
20 nmole Ultramer™ DNA Plate Oligo 63,00 € EUR Add To Order
Structure
Structure